anastrozole for men

Over 90% of ingested phospholipids absorbed in the small intestine. Most of them are cleaved by phospholipase A to 1-acetyl-lysophosphatidylcholine, 50% of which is inversely acetylation in polyunsaturated phosphatidylcholine during absorption in the intestinal mucosa. With anastrozole for men polyunsaturated phosphatidylcholine lymph current into the bloodstream, where, mainly associated with high density lipoproteins to the liver form. The pharmacokinetics in humans has been studied using dilenoleil radiolabeled (choline part) and 14 C (linoleic acid residue). The maximum concentration, accounting for 19.9% of the administered dose; 14 C – after 4-12 hours, accounting for 27.9%. The half-life choline component is 66 hours, the residue of linoleic acid – 32 hours. The feces ; in urine – 6% 3 H and the minimum quantity S. Both isotopes absorbed in the gut more than 90%. glycyrrhizic acid Following oral administration in the gut by enzymes produced by bacteria of normal flora, glycyrrhizic acid is formed from an active , which is absorbed into the systemic circulation. The blood ß-glycyrrhetic acid is bound to albumin, and is almost entirely transported to the liver. Isolation of ß-glycyrrhetic acid occurs mainly in the bile, the residual amount -. With urine from the experimental data, the phospholipids improve lipophilic properties of glycyrrhizin acid, increasing the intensity and speed of its absorption of more than 2 times.


  • Fatty degeneration of the liver (steatosis), alcoholic, toxic, including drugs, liver damage;
  • In the combined therapy of viral hepatitis (acute and chronic), liver cirrhosis and psoriasis.


  • Hypersensitivity to anastrozole for men glycyrrhizic acid, phosphatidylcholine, or other components of the drug;
  • Antiphospholipid syndrome;
  • Pregnancy (safety and efficacy data are not enough);
  • The period of breastfeeding (on efficacy and safety data are not sufficient);
  • Children under 12 years of age (efficacy and safety data are not sufficient).

Be wary . In patients with portal hypertension. In patients with hypertension. In the presence of these diseases, before taking the drug anastrozole dosage should consult a doctor.

Dosing and Administration

Inside, during a meal, not liquid, squeezed small amounts of liquid. The recommended dosing regimen in adults and children over 12 years – 2 capsules 3 times a day. Duration of treatment may be up to 6 months, on average – 3 months.

Side effect

Usually Phosphogliv drug is well tolerated, side effects develop very rare, according to post-marketing surveillance – frequency <1/10000. Allergic reactions : skin rash, difficulty in nasal breathing, conjunctivitis, cough. Cardio-vascular system : transient (transient) increase in blood pressure, peripheral edema. On the part of the digestive system :. dyspepsia (burping, nausea, bloating), abdominal discomfort should stop taking the drug and consult a doctor if you experience these symptoms.


No cases of overdose have been reported.

special instructions

In the case of high blood pressure anastrozole for men should stop taking the drug and consult a doctor.

Effects on ability to drive vehicles and mechanisms

The drug has no negative impact on the ability to drive and perform other tasks that require high concentration and speed of psychomotor reactions.